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The Food and Drug Administration on Thursday approved the first prescription drug, Eli Lilly's Cialis, to treat erectile dysfunction. According to the new warning, men who take the drug should be advised of the potential side effects such as vision loss, increased sweating, and nasal congestion. Cialis should be used only by men under 18 years of age.

The drug, which was first approved by the FDA in 1998, works by blocking an enzyme called phosphodiesterase type 5 (PDE5). This enzyme is responsible for breaking down a chemical called cyclic guanosine monophosphate (cGMP), which is needed by a variety of body tissues. Cialis has long been used to treat erectile dysfunction. However, studies have shown that Cialis may cause some side effects, including dizziness, flushing, headaches, and blurred vision.

Cialis can cause vision loss if you are over the age of 18 and use nitrates or nitric oxide donors such as generic nitroglycerin. In addition, some people may experience some side effects after taking the drug.

According to a news release from Lilly, the drug has been linked to a dangerous increase in the risk of heart attack, stroke, and death in people who use nitrates for chest pain. Lilly is working with the FDA to take action to warn patients of this risk, so that more people can use the drug safely.

The FDA is also requiring the company to make a statement that its warning is based on a review of the safety and efficacy of the drug.

In the news release, Cialis also warns patients against taking Cialis and encourages them to take it as directed by their healthcare provider.

Cialis has been linked to severe dizziness, fainting, and heart attack in people who take nitrates for chest pain. People with a history of heart attack, stroke, or blood clots may also be at risk.

Cialis has also been linked to the potential for severe stomach or intestinal ulcers, bleeding, and perforation in people who take nitrates for angina. The drug may also cause kidney failure and may even cause an increased risk of blood clots. The drug can also increase the risk of stroke in people who have had heart attacks, blood clots, and blood vessel disease.

The FDA also warns that if you use the drug for more than 14 days after taking nitrates for angina, you should stop taking Cialis and call your doctor right away. The FDA also warns against using Cialis for more than 14 days after you start taking nitrates for angina. If you have any symptoms of a heart attack or stroke while taking Cialis, you should call your doctor right away.

According to the FDA, Cialis should not be used for erectile dysfunction. The drug is not intended for use by men under the age of 18. The warning has been added to the product labeling and has not been updated.

The FDA also added the word “sudden cardiac death.” The drug is also being studied as a potential treatment for men who have heart failure.

The FDA also warned about possible side effects of Cialis. The drug may cause dizziness, fainting, and heart attack in people who use nitrates for angina. Cialis can also cause vision loss, high blood pressure, and high cholesterol. Patients should be advised to stop taking the drug and call their doctor if they experience any of these symptoms.

The FDA also warned that patients taking nitrates for angina should seek medical attention right away if they experience any of the following symptoms:

• Blood clots in their legs or ankles

• Blood clots in their feet or ankles

• Chest pain

• Flushing

• Nasal congestion

• Nausea

• Diarrhea

• Swelling of ankles or legs

• Stomach cramps

• Swelling of the ankles or legs

• Heart attack symptoms

• Stroke symptoms

• Seizures

• Liver damage

• Increased risk of death in people taking nitrates for angina

The FDA also warned that the risk of getting heart attacks, strokes, blood clots, and heart attacks in people taking nitrates for angina has been increased.

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Erectile Dysfunction

Erectile dysfunction (ED) is a common condition that affects men of all ages. The condition includes both men and women. Theetchup offers several effective solutions for those affected by ED.

Tadalafil

is a phosphodiesterase (PDE) inhibitor commonly used to treat erectile dysfunction. It works by increasing blood flow to the penis during sexual stimulation, helping men achieve and maintain an erection. Tadalafil is available online through various brand names such as Cialis, PDE5, and Spedra.

Sildenafil

It works by helping to increase blood flow to the penis, which may be difficult for men with diabetes. Sildenafil is available online through various brand names, including PDE5 and PDE5. Take an approach to getting the most benefit from sildenafil, particularly when treating erectile dysfunction.

It works by helping to increase blood flow, which may be difficult for men with diabetes. Tadalafil is available online through various brand names, including Cialis, PDE5, and Spedra. For men who have not responded to other PDE5 inhibitors, tadalafil can be used to treat erectile dysfunction.

We have with us superior quality Cialis (Tadalafil) which are well known among our customers for their high efficiency. Our offered medicines are primarily used for treating...

How to use Cialis (Tadalafil)?

Using Cialis (Tadalafil) can produce the following results:

  • Erection will occur within 30 minutes
  • One tablet should be taken an hour before sexual activity
  • The effects should be felt within 4 hours
  • Increased libido...
  • Erection will occur within 30 minutes.

How to take Cialis (Tadalafil)

The recommended dose of Cialis (Tadalafil) is 50mg taken approximately one hour before sexual activity. Cialis (Tadalafil) is usually taken approximately one to three hours before sexual activity. Please take it on an empty...

Warnings & Side Effects

Do not take Cialis (Tadalafil) if:

  • You are allergic to Tadalafil or any of the other ingredients of this medicine
  • You have been advised by your doctor to avoid sexual activity because of a problem with your kidneys or dizziness
  • You have low blood pressure
  • You have severe kidney problems
  • You have heart problems such as heart failure, or a heart attack, etc.

Warnings to keep Cialis (Tadalafil inhibitor

Do not share this medicine with others.

Do not take Cialis (Tadalafil) if you:

  • Are undergoing kidney function tests
  • Have severe liver problems
  • Have recently lost a large amount of body fluids
  • Have heart problems
  • Are 65 years or older
  • Have very low blood pressure
  • Are ageist people

You should not use Cialis (Tadalafil) if you:

  • Have ever had an erection that lasted more than 4 hours
  • Have a firmblood pressure (hypertension) problem
  • Have a heart problem which is old agea high cholesterol
  • Have a vision problem
  • Have an eye problem such as retinitis pigmentosa
  • Have a face problem with the formation of...
  • Have a low blood pressure
  • Have a low blood pressure (below 90/50) or are not taking...
  • Are taking alpha blockers such as alfuzosin (Uroxatral), doxazosin (Cardura), tamsulosin (Nexium) or dapoxetine (Rapaflo) in the last 6 months of pregnancy
  • Have a stomach ulcer or a bleeding disorder
  • Have ever had a...
  • Have a problem with your kidneys or dizziness
  • Have a problem with your...
  • Have an eye problem with the formation of...

Consult your doctor if you:

  • Have kidney problems
  • Take more than one tablet per day
  • Take sexual...
  • Take different medicines
  • Have a stomach ulcer or bleeding disorder
  • Have AGE (e.g. low...
  • Have a problem with your heart
  • Are not taking any other medicines
  • Are not taking any medicines for...
  • Take regular medicines
  • Take other medicines that are combined with Cialis (Tadalafil)
  • Have a problem with...

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Cialis (tadalafil) can interact with certain foods and beverages, so be sure to beibu aware of both Cialis and grapefruit juice as well as alcohol. Avoid consuming grapefruit or grapefruit juice while taking Cialis, as these two substances may increase the level of tadalafil in your blood. Closely monitor your blood pressure if using Cialis.

Note:

This article is for guidance only and does not, and should not be taken by the Pharmacist, the Patient, or the pharmacist. It is not intended as a substitute for professional medical advice, treatment, or professional guidance. It is not a substitute for honest feelings about yourself and your well-being.